Thursday, January 29, 2026

The Daily Market Flux - Your Complete Market Rundown (01/29/2026)

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Here is Your Complete Market Rundown (01/29/2026)

Top Stories:

Bitcoin Struggles Near $88K as Gold Surges and Long-Term Holders Exit

Bitcoin faces mounting pressure as long-term holders sell amid Friday’s $9 billion options expiry, while gold adds Bitcoin’s entire market cap in 72 hours. The cryptocurrency’s “digital gold” narrative weakens as traders pivot to metals despite the dollar’s worst run in eight years failing to lift BTC prices.

Trump and Schumer Near Shutdown Deal as Border Official Ousted, Fraud Division Created

President Trump and Senator Schumer are moving toward an agreement to prevent a government shutdown. Separately, senior Border Patrol official Gregory Bovino was removed January 27 after leading Operation Metro Surge in Minneapolis. Trump also nominated Colin MacDonald to head a new Justice Department fraud enforcement division on January 8.

Company News

Microsoft Corporation (MSFT)

Performance Overview

1D Change: -10.02%

5D Change: -3.84%

News Volume: 309

Unusual Volume Factor: 8x

Microsoft Shares Plunge 12% in Worst Day Since 2020 as AI Spending Concerns Overshadow Strong Earnings

Microsoft reported strong second-quarter fiscal 2026 results that beat earnings estimates, with record cloud revenue and 60% profit growth, yet shares tumbled 12% on January 29 in the company’s steepest decline since March 2020. The selloff erased approximately $357 billion in market capitalization, marking the second-largest single-day value destruction in stock market history. The decline stemmed from investor concerns over the company’s record-high AI capital expenditures and slower-than-expected Azure cloud growth.

Microsoft outlined a third-quarter revenue target of $80.65 billion to $81.75 billion amid accelerating AI cloud demand and Copilot seat growth, but the guidance failed to satisfy investors demanding clearer returns on massive AI investments. Wall Street analysts responded with widespread price target reductions. Goldman Sachs lowered its target to $600 from $655, JPMorgan cut to $550 from $630, and Morgan Stanley removed Microsoft as a top pick. However, most firms maintained positive ratings, with analysts at Deutsche Bank, BMO Capital, and others emphasizing the company’s long-term AI positioning despite near-term spending concerns.

The Microsoft decline triggered a broader software sector selloff, with the sector entering bear market territory. The company’s weakness stood in stark contrast to Meta Platforms, which surged 8% after demonstrating clearer AI monetization in its advertising business. This divergence highlighted growing investor impatience with AI spending that has yet to produce proportional returns, though several analysts urged investors to view the dip as a buying opportunity.

The company reported it spent record amounts on AI infrastructure in the quarter and announced it would continue purchasing chips from Nvidia and AMD even after launching its own processors. Microsoft also disclosed that AI startup Perplexity signed a $750 million cloud deal to use Azure services. Reports emerged that Microsoft, along with Nvidia and Amazon, is in talks to invest tens of billions in OpenAI, with Microsoft’s contribution expected to be under $10 billion. The Federal Reserve’s decision to hold rates steady provided a backdrop to the tech earnings, while gold hit record highs as investors reassessed risk.

Tesla, Inc. (TSLA)

Performance Overview

1D Change: -3.45%

5D Change: -7.27%

News Volume: 246

Unusual Volume Factor: 3x

Tesla Pivots to Robotics and AI as EV Sales Decline, Plans Record $20 Billion Capital Spending

Tesla reported its first annual revenue decline on record alongside a 61% drop in Q4 profit, yet shares rose modestly following the company’s earnings call outlining an aggressive pivot toward artificial intelligence and robotics. The automaker announced plans to discontinue production of its Model S and Model X vehicles to redirect manufacturing capacity toward its Optimus humanoid robot, while more than doubling capital expenditures to over $20 billion in 2026—with the majority allocated to robotaxis and robotics rather than traditional vehicle production. The company confirmed a $2 billion investment in CEO Elon Musk’s AI firm xAI, signed January 16, and reiterated that Cybercab robotaxi production remains on track for this year.

Musk positioned Tesla as a “physical AI company” focused on “transportation-as-a-service,” proposing that Tesla owners could eventually lend their self-driving vehicles to a robotaxi fleet. The company also disclosed active Full Self-Driving subscription numbers globally for the first time as Musk pursues a goal of 10 million users. Wall Street analysts delivered mixed reactions to the strategic shift. While several firms maintained bullish ratings—Cantor Fitzgerald reiterated its $510 target and Mizuho raised its target to $540—others expressed skepticism about the transition away from core automotive business.

Goldman Sachs lowered its price target to $405, Morgan Stanley reduced its target to $415, and Truist cut its outlook to $438, citing concerns about production changes and execution risks. Analysts at Jefferies called it the “most interesting earnings call in many quarters,” while others questioned whether the ambitious robotics vision could offset declining vehicle sales. Tesla’s energy storage division emerged as a bright spot, growing faster than any other business segment, with the company selling $430 million worth of Megapack batteries to xAI in 2025.

However, the company faces intensifying competition in electric vehicles, particularly from BYD in Europe, where EVs have surpassed gasoline market share. First Solar shares dropped 13% on concerns that Tesla’s potential solar expansion could pressure the sector. Adding complexity to Tesla’s outlook, reports emerged that SpaceX and xAI are in merger discussions ahead of a planned SpaceX IPO, potentially further intertwining Musk’s business empire. Musk emphasized “geopolitical risk” as justification for Tesla’s TeraFab chip-building initiative and massive capital spending plans, though some analysts warned the company could return to cash-burn mode as it pursues its costly AI vision.

Meta Platforms, Inc. (META)

Performance Overview

1D Change: 10.53%

5D Change: 14.01%

News Volume: 249

Unusual Volume Factor: 4x

Meta Surges 8% on Strong Q4 Beat as $135 Billion AI Spending Plan Wins Wall Street Approval

Meta Platforms delivered a standout earnings performance that sent shares soaring over 8% in their biggest single-day gain since July 2025, sharply contrasting with Microsoft’s 11% plunge. The Facebook parent reported record Q4 sales that beat expectations and issued first-quarter revenue guidance above Wall Street forecasts, demonstrating that its advertising business remains robust despite massive technology investments. The company announced plans to spend up to $135 billion on AI infrastructure in 2026, representing a 73% increase and nearly double last year’s capital expenditure. This figure exceeds initial analyst expectations by roughly 20% and could fund 90 NFL stadiums or rival New York’s annual budget. Rather than spooking investors as similar announcements have for competitors, Meta’s spending plan received widespread analyst support, with at least 15 firms raising price targets. Jefferies set the highest target at $1,000 per share, while multiple banks including Deutsche Bank, Evercore ISI, and Wedbush raised targets to $900.

CEO Mark Zuckerberg framed the spending as a pursuit of “superintelligence” and touted a “major AI acceleration,” emphasizing that AI tools are already enabling individual employees to accomplish work previously requiring large teams. Crucially, Meta demonstrated tangible returns from AI investments through improved ad targeting and business performance, addressing investor concerns about when heavy AI spending will generate profits. Analysts highlighted that Meta is showing clearer monetization paths than peers, with its AI-enhanced advertising platform driving measurable revenue gains. The strong results propelled Zuckerberg past Jeff Bezos to become the world’s fourth-richest person. Wall Street characterized Meta’s performance as evidence the company has found its way back into investor favor by proving its cash engine works even under peak AI spending, though some analysts cautioned the stock may be “priced for perfection” following the rally. The Federal Reserve’s decision to hold rates steady provided a supportive backdrop for the earnings reaction, with Meta standing out among the Magnificent Seven as Tesla posted modest gains and Microsoft disappointed on cloud growth concerns.

International Business Machines Corporation (IBM)

Performance Overview

1D Change: 4.95%

5D Change: 4.85%

IBM Stock Surges 8% on Strong Q4 Earnings Beat, Analysts Raise Price Targets Across the Board

IBM shares jumped approximately 8-9% in Thursday trading after the company exceeded fourth-quarter expectations, driven by surprisingly strong software growth and expanding artificial intelligence momentum. The company reported its AI book of business now exceeds $12.5 billion and issued 2026 guidance well above Street forecasts. Wall Street analysts responded with widespread price target increases. JPMorgan raised its target to $317, citing strong software growth, while BMO Capital lifted its target to $350. Wedbush increased its target to $340, Jefferies to $370, and Oppenheimer to $380. RBC Capital set a $361 target, and Evercore ISI upgraded the stock to Outperform with a $345 target. UBS raised its target to $236 while maintaining a Sell rating.

IBM also unveiled new research showcasing its vision for quantum computing, with implications for how the technology might integrate with offerings from Nvidia and AMD. The company kicked off a big tech debt spree with dollar and euro bond issuances. Moody’s affirmed IBM’s A3 credit ratings and changed the outlook to stable.

The earnings performance stood out on a mixed day for major tech companies, with Microsoft falling 6.5% and Meta Platforms rising 7.9%. IBM’s software segment strength particularly impressed analysts, with the company demonstrating momentum in its AI-driven transformation strategy.

Former IBM executive Ayman Antoun was named CEO of OpenText, highlighting IBM’s continued influence in the enterprise technology sector. The stock’s performance made it one of Thursday’s biggest market movers, appearing on multiple premarket gainers lists alongside Meta Platforms and Tesla.

Technology Events

Apple Acquires Israeli AI Startup Q.ai for Nearly $2 Billion

Apple has purchased Israeli artificial intelligence startup Q.ai, which specializes in audio technology and facial movement interpretation, in a deal valued at approximately $2 billion, marking the company's first major acquisition in several years.

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Amazon in Talks for Up to $50 Billion OpenAI Investment

Amazon is reportedly negotiating a potential investment of up to $50 billion in OpenAI, with the deal possibly materializing in the coming weeks, according to sources and WSJ reports.

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AI Infrastructure and Agentic Applications Drive Market Momentum Amid Control Concerns

Celestica emerges as de-risked AI infrastructure play while ServiceNow positions for agentic AI growth. ASE Technology advances on AI-driven demand. Silicon Valley forum emphasizes preserving US AI leadership as Google DeepMind addresses responsible AI development. Mixed stock results follow AI spending surge, while viral app Moltbot previews AI agent capabilities.

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Perplexity Signs $750 Million Microsoft Azure Deal Amid Amazon Legal Dispute

AI startup Perplexity has secured a $750 million cloud services agreement with Microsoft Azure, marking a significant shift from its longtime partnership with Amazon amid an ongoing legal dispute between the two companies.

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Crypto Events

Senate Agriculture Committee Advances Crypto Bill Establishing CFTC Oversight

The US Senate Agriculture Committee has advanced a long-awaited crypto market structure bill that would establish CFTC regulatory authority over digital assets, though the legislation faces obstacles ahead despite this initial progress.

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Metaplanet Approves $137M Capital Raise for Bitcoin Expansion

Japanese firm Metaplanet plans to raise $137 million through overseas offering to increase Bitcoin holdings and reduce debt obligations.

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Bitcoin Drops Below $85,000 as Liquidity Crunch Triggers $430 Million in Liquidations

Bitcoin fell to $85,887 on January 29, marking its lowest level in six weeks as thin liquidity amplified selling pressure. The decline accelerated after U.S. markets opened, with the cryptocurrency dropping roughly 2% from $88,000. Over $430 million in crypto positions were liquidated within 60 minutes, including $150 million in long positions. The broader crypto market followed suit, with Ethereum falling below $2,900, BNB under $600, and Solana dropping below $120 amid a wider pullback in risk assets.

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Geopolitics Events

Trump and Schumer Near Shutdown Deal as Border Official Ousted and Fraud Division Launched

President Trump and Senate Majority Leader Chuck Schumer are moving toward an agreement to avert a government shutdown, according to the New York Times. The development comes amid significant personnel changes in the administration. On January 27, 2026, senior Border Patrol official Gregory Bovino was removed following the collapse of Operation Metro Surge in Minneapolis, which had deployed thousands of agents for mass enforcement operations. Earlier in January, Trump nominated Colin MacDonald to lead a new Division for National Fraud Enforcement at the Justice Department, targeting large-scale fraud. In foreign policy, Secretary of State Marco Rubio indicated Venezuela's new leadership is pursuing closer Washington ties, reducing immediate need for military action following Nicolas Maduro's capture. Meanwhile, gold prices surged past $5,500 amid tensions with Iran, and the administration backed away from plans to guarantee minimum prices for critical minerals projects, citing funding constraints and market complexity concerns.

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Trump Announces Venezuela Airspace Reopening as Shutdown Talks Progress

President Trump announced Thursday the immediate reopening of commercial airspace over Venezuela following a call with the country's acting president, marking a significant shift in U.S.-Venezuela relations after the raid to capture Nicolas Maduro. Major oil companies will scout locations in Venezuela, and Trump said Americans will be able to visit the country shortly. American Airlines plans to resume daily service pending government approval and security assessments. The announcement came during a White House cabinet meeting where Trump also addressed the looming government shutdown deadline. Trump stated he hopes to avoid a shutdown and will work in a bipartisan manner, saying Democrats don't want one either. Senate Majority Leader Chuck Schumer and Trump are moving toward an agreement, with Senate Republican Leader Thune saying talks are going in the right direction. Under the emerging deal, the Department of Homeland Security would receive stopgap funding, splitting off contentious immigration enforcement provisions from the broader spending package. Markets initially priced a 73 percent chance of shutdown by January 31, though odds have since fallen as deal prospects improved. The Senate is expected to vote on advancing six remaining spending bills funding major government departments through September 30. Trump also announced he will name the next Federal Reserve head next week and called for immediate rate cuts of two to three percentage points, arguing high rates harm the economy and national security. The comments came after the FOMC held rates steady. Trump separately noted the S&P 500 hit 7,000 for the first time.

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Trump Escalates Fed Criticism as Trade Deficit Hits 1992 Record While ICE Operations Face Pushback

President Trump intensified his attacks on Federal Reserve Chair Jerome Powell, demanding the U.S. maintain the lowest interest rates globally and calling Powell "too late" for refusing rate cuts. Trump argued tariff revenues justify lower rates, stating he has been "gentle" to countries but could bring more money to the U.S. with a "mere flip of the pen." The U.S. trade deficit widened month-over-month by the most since 1992 in November, rebounding from 2009 lows as imports surged and exports declined amid volatile responses to Trump's shifting tariff policies. Oil prices rose over 2% as Trump weighs potential strikes on Iran, adding geopolitical tension to market concerns. Immigration enforcement operations faced significant complications as ICE scaled back enhanced activities in Minnesota and Maine following local resistance. Border czar Tom Homan announced federal agents would be drawn down from Minneapolis, with further reductions possible if local cooperation improves. The administration's aggressive Minnesota operations, which deployed thousands of federal agents ostensibly targeting Somali immigration, drew criticism as politically motivated rather than operationally necessary. Corporate America navigated an increasingly complex political landscape. Minnesota CEOs weighed risks of speaking out against Trump's policies amid what some described as a "climate of fear," while GM's ability to balance profits and politics under the administration paid dividends for investors. Senate Democrats demanded new ICE limits in exchange for avoiding a government shutdown, with Senator Ron Wyden questioning Trump's acceptance of luxury gifts from Swiss businessmen before reducing Swiss tariffs. Regional tensions persisted as Balkan truck drivers maintained EU border blockades and ASEAN ministers addressed Myanmar's conflict and South China Sea negotiations.

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US Trade Deficit Nearly Doubles to $56.8 Billion, Exceeding Forecasts

The US trade deficit surged to $56.8 billion in November, up 94.6% from October's revised $29.2 billion and far exceeding the $44 billion forecast. The goods deficit jumped $27.9 billion to $86.9 billion as imports rebounded and exports declined, marking a sharp reversal from October's smallest deficit since 2009 amid volatile monthly swings tied to fluctuating tariff policies.

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Trump to Announce Federal Reserve Chair Nominee Next Week

President Trump will unveil his choice for Federal Reserve Chair next week, signaling an imminent replacement for current Chair Jerome Powell. The announcement comes as Congress faces a potential government shutdown, adding significance to the timing of this key economic policy decision.

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Senate Blocks Funding Bill as Shutdown Looms Over Immigration Dispute

Senate Democrats blocked a government funding package in a procedural vote, pushing federal agencies toward shutdown. The impasse centers on immigration enforcement provisions. The White House and Senate Democrats are negotiating a potential compromise that would separate immigration funding from the broader spending bill to break the deadlock before the deadline.

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Trump Announces Week-Long Pause in Russian Strikes on Ukrainian Cities

President Trump said Russian President Putin agreed to halt bombing of Ukrainian cities and towns for one week amid record cold temperatures. The temporary cessation specifically covers Kyiv and other population centers as Ukraine braces for extreme winter weather.

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China Accelerates Green Investment and Service Sector Growth as UK Signals Economic Reset

China announced major infrastructure and economic initiatives, including a 65 billion yuan investment in pumped hydro storage through 2030 to support renewable energy expansion. The country's green finance sector has grown to $6.8 trillion over the past decade. Beijing unveiled plans to boost domestic services consumption while tightening its $86 billion Mutual Recognition of Funds program to limit mainland investor flows into foreign markets. Prime Minister Keir Starmer met with President Xi Jinping, signaling improved UK-China relations with progress reported on tariffs, travel, and migration. AstraZeneca committed $15 billion to expand Chinese operations through 2030, reflecting continued foreign investment despite regulatory adjustments.

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Trump Immigration Standoff Threatens Government Shutdown as Iran Tensions Escalate

A potential government shutdown looms at midnight January 31st over disputes regarding President Trump's immigration enforcement activities. Trump and Senator Chuck Schumer are negotiating new restrictions on federal immigration agents to avert the crisis, while ICE officers in Minnesota received guidance to avoid confrontations with agitators during enforcement operations. Separately, Trump is considering airstrikes on Iran's nuclear sites and leadership after preliminary talks stalled over Tehran's refusal to limit ballistic missile range. Iran has vowed immediate retaliation. On the domestic front, Treasury Secretary Bessent defended Trump's financial accounts as rainy day funds, receiving backing from JPMorgan and Bank of America. German Chancellor Merz signaled European resistance to Trump's pressure tactics, while Russia awaits a US response on extending the New START treaty.

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China Military Purge Continues as Xi Reshapes Armed Forces; UK, Vietnam Seek Stronger Ties with Beijing and EU

China's military is undergoing a major restructuring under President Xi Jinping, with numerous senior generals being removed from their positions. The nation announced plans to develop space tourism and deep space exploration amid intensifying competition with the US, which extends to cyber espionage where leaked documents reveal China's advancing capabilities. China forecasts a record 9.5 billion passenger trips during the spring festival travel period. Meanwhile, British Prime Minister Keir Starmer met with Xi to pursue a "sophisticated relationship" aimed at economic growth and security, marking a potential thaw in UK-China relations. Separately, Vietnam and the European Union elevated their diplomatic partnership to comprehensive strategic status, focusing on semiconductors, critical materials, and trade cooperation.

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China Restricts Cross-Border Investment Program Amid Rising Global Demand

China has tightened its $86 billion Mutual Recognition of Funds program, limiting where global asset managers can allocate mainland client funds, particularly curbing flows into US markets. The move aims to protect retail investors as demand surges. Meanwhile, diplomatic efforts continue as UK Prime Minister Keir Starmer met with President Xi Jinping, reporting progress on tariffs and trade issues. China's Commerce Ministry expressed willingness to use bilateral trade mechanisms with the US to manage differences, as Western powers navigate Trump-era trade tensions by rebalancing relations with Beijing.

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Trump Defends Closing Eyes During Cabinet Meeting, Calls Session 'Boring'

President Trump addressed criticism about appearing to doze during a recent Cabinet meeting, stating he closed his eyes because the session was "pretty boring" but insisted he did not sleep. Trump concluded today's Cabinet meeting without taking reporters' questions.

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Macro Events

Fed Rate Pause Triggers Market Volatility as Investors Recalibrate Expectations

The Federal Reserve's decision to hold rates steady has rippled through global markets, with investors now anticipating delayed rate cuts beyond Chair Jerome Powell's May term end. Emerging markets paused their five-day rally as the dollar stabilized, while Indonesia suffered its worst stock selloff in twenty years. Housing data showed deflationary pressure with January rents declining 0.2% monthly and 1.4% annually. Foreign portfolio investment flows remained volatile amid global uncertainty and capital migration toward AI-focused markets, according to the Economic Survey.

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US Jobless Claims Edge Down to 209,000, Missing Forecasts but Signaling Labor Market Stability

US initial jobless claims fell modestly to 209,000 for the week ending January 24, down 1,000 from the prior week's revised 210,000. The figure came in above the expected 205,000, marking a slight miss on forecasts. Continuing claims for the week of January 17 declined 38,000 to 1.827 million, while the insured unemployment rate held steady at 1.2 percent. The four-week moving average rose 2,250 to 206,250, suggesting some stabilization in the labor market despite elevated layoff levels.

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Corporate Actions Events

SpaceX and xAI Explore Merger Ahead of Planned IPO

Elon Musk's SpaceX and artificial intelligence company xAI are in merger discussions before a planned public offering later this year, according to reports. The potential combination would consolidate SpaceX, Starlink, X, and Grok AI operations under one entity.

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Coterra Energy and Devon Energy in Advanced Merger Talks

Coterra Energy and Devon Energy are discussing a combination that would rank among the largest recent oil and gas deals, while US lawmakers scrutinize trading firms' Venezuela operations amid easing state oil controls.

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Earnings Events

Western Digital Beats Q2 Earnings Expectations on AI Demand

Western Digital reported second-quarter earnings of $2.13 per share versus $1.91 forecast, with revenue reaching $3.1 billion against $2.92 billion estimates, driving shares higher amid AI-driven momentum.

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Major Q4 2025 Earnings Reports Released Across Multiple Sectors

Several major companies including Meta Platforms, Dow, Lazard, Xerox, Deluxe, Axfood AB, and Altria reported fourth quarter 2025 earnings, with Altria missing EPS expectations and experiencing a stock decline.

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SanDisk Shares Soar on Strong Q2 Earnings Beat and Robust Q3 Guidance

SanDisk stock surged after reporting second-quarter results that exceeded expectations, with earnings beating estimates by $2.71 and revenue topping forecasts, driven by AI demand for memory chips.

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Visa Beats Q1 Earnings Expectations But Stock Falls on Transaction Volume Concerns

Visa reported first-quarter earnings that exceeded analyst expectations, driven by stronger consumer spending. However, shares declined as the number of processed transactions fell short of forecasts, raising concerns about underlying payment volume growth despite the earnings beat.

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Oil And Gas Events

Oil Prices Surge Nearly 5% on Potential U.S. Strike Against Iran

Brent crude jumped 5% to August 2024 highs while U.S. oil prices climbed nearly 5% amid growing market concerns that President Trump may authorize military strikes on Iran, marking the sharpest single-day gain in months.

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Major Energy Shifts as Venezuela Returns to Market and Mozambique LNG Restarts

Valero Energy will purchase Venezuelan crude from three authorized sellers, marking a significant return since 2019 sanctions, with processing capacity expected to exceed 240,000 barrels daily in February and March. TotalEnergies announced the full restart of its Mozambique LNG project after years of delay. Meanwhile, Colombia's largest pipeline operator plans a global LNG tender for its Ballena terminal, scheduled for 2027, to address growing gas supply gaps and reduce import costs.

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Venezuelan Lawmakers Approve Major Oil Sector Privatization Despite Skepticism

Venezuela's parliament passed legislation to reduce state control and open its oil industry to private firms, prompting Washington scrutiny and skepticism from oil executives despite Secretary Rubio's congressional reassurances.

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Currencies Events

Rare-Earth ETFs Retreat While Dollar Weakness and Robinhood's Trump Account Role Dominate Markets

Leveraged rare-earth ETFs declined following their Trump deal rally. The weakening dollar raises concerns for Trump's agenda and Fed chair succession. Robinhood shares surged on reports the US government may select the platform to manage new "Trump accounts" being created for millions of children.

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Healthcare Events

FDA Accepts Drug Applications from Unicycive and Summit Therapeutics

Unicycive and Summit Therapeutics gained after FDA accepted their drug applications. Summit's ivonescimab targets lung cancer patients with specific genetic mutations, with decision expected November 2026.

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Pharma Sector Sees Strategic Moves as Companies Position for Growth

Aurobindo Pharma faces minimum import price regulations on key antibiotics including PenG and Amoxicillin. Palisade Bio strengthens its inflammatory bowel disease program by adding prominent gastroenterology experts to guide PALI-2108's Phase 2 development. Meanwhile, Aspire Biopharma advances sublingual aspirin technology through new partnership, and Roche pursues obesity market entry to compete with established leaders.

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Kennedy's Policy Shifts Spark Parental Concerns Over Newborn Care; Sanofi Vaccines Face U.S. Headwinds

Health Secretary Robert F. Kennedy Jr.'s policy changes are driving increased parental hesitancy toward routine newborn treatments, including vitamin K and eye ointment. Sanofi's vaccine sales confront challenges from U.S. policy shifts. Meanwhile, Fractyl Health shares declined following midpoint data on GLP-1 weight maintenance, while GUTS seeks FDA guidance on reclassifying Revita through the De Novo pathway.

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Biotech Stocks Decline on Disappointing Clinical Trial Results

Sagimet fell 4.1% premarket after its Chinese partner released late-stage acne therapy data, while Aprea Therapeutics dropped following early-stage cancer drug results.

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Fixed Income And Interest Rates Events

Wall Street Prepares Record February Bond Sales for AI Projects Amid Market Concerns

Corporate bond issuance may hit record levels in February as Wall Street finances AI infrastructure expansion. Meanwhile, Treasury markets remain volatile ahead of US jobs data, Japanese yields rise with global implications, and analysts recommend rotating away from short-term bonds.

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