What "event" will be the nail in the coffin for your Bitcoin goals?

lot of people have their breaking point, where they will throw in the towel. What "event" or "change in technology" will be
your final nail in the coffin for your Bitcoin dreams? A lot of people are looking at the Bitcoin price as a trigger, but that would
be stupid. (The price are mostly manipulated, so this is a bad guideline)
The trigger must be something other than the price. (Example : Major change in the Bitcoin code / Core developer leaving /Flaw in the protocol / The introduction of a much better technology etc.)